ProSci

Transthyretin Recombinant Protein

Product Code:
 
PSI-96-756
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
 

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PSI-96-756-0.1mg0.1mg£597.00
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Further Information

Additional Names:
Transthyretin, TTR, Prealbumin, TBPA, ATTR, PALB, CTS, CTS1, HsT2651
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Transthyretin (TTR) is also known as Prealbumin, ATTR, TBPA, PALB, which belongs to the transthyretin family. Transthyretin / TTR is a serum and cerebrospinal fluid carrier of the thyroid hormone thyroxine (T4) and retinol-binding protein bound to retinol. In cerebrospinal fluid TTR is the primary carrier of T4. TTR also acts as a carrier of retinol (vitamin A) through its association with retinol-binding protein (RBP) in the blood and the CSF. Less than 1% of TTR's T4 binding sites are occupied in blood. TTR misfolding and aggregation is known to be associated with the amyloid diseases.
Background References:
  • Getz R.K., et al., 1999, Exp. Eye Res. 68:629-636.
  • Herbert J., et al., 1986, Neurology 36:900-911.
  • Mita S., et al., 1984, Biochem. Biophys. Res. Commun. 124:558-564.
Biological Activity:
Measured by its ability to bind biotinylated human RBP4 in a functional ELISA.
Buffer:
PBS, pH7.4
Fusion Tag:
His Tag
NCBI Gene ID #:
7276
NCBI Official Name:
transthyretin
NCBI Official Symbol:
TTR
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
14.6 kDa
Protein Accession #:
NP_000362
Purity:
>95% as determined by SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
P02766

Documents