ProSci

Contactin 2 Recombinant Protein

Product Code:
 
PSI-96-193
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
 

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PSI-96-193-0.1mg0.1mg£765.00
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Further Information

Additional Names:
CNTN2, AXT, DKFZp781D102, FLJ37193, FLJ42746, MGC157722, TAG-1, TAX, TAX1, Contactin-2
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Contactin-2 is also known as CNTN2, TAX1 (transiently-expressed axonal glycoprotein), TAG1 (transient axonal glycoprotein), and axonin-1, and is a member of the immunoglobulin superfamily. CNTN2 consists of six Ig-like domains and four fibronectin type III domains, and is anchored to the membrane by glycosylphosphatidylinositol (GPI), whereas the soluble form can be released by a GPI-specific phospholipase. As a neural cell adhesion molecule expressed by a subset of neuronal populations in the developing CNS and PNS, CNTN2 mediates cell-cell interactions either via homophilic, or heterophilic contacts with various adhesion molecules including NgCAM, NrCAM, NCAM and neurocan. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. It may also be involved in glial tumorigenesis and may provide a potential target for therapeutic intervention.
Background References:
  • Tsiotra PC, et al., 1993, Genomics 18 (3): 562?7. .
  • Traka, M. et al., 2003, J. Cell. Biol. 162: 1161-1172.
  • M?rtl M, ET AL., 2007, Protein Sci.16(10):2174-83.
Buffer:
PBS, pH7.4
Fusion Tag:
His Tag
NCBI Gene ID #:
6900
NCBI Official Name:
contactin 2 (axonal)
NCBI Official Symbol:
CNTN2
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
109 kDa
Protein Accession #:
NP_005067.1
Purity:
>95% as determined by SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
Q02246

Documents