ProSci

FN14 Recombinant Protein

Product Code:
 
PSI-96-735
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
 

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PSI-96-735-0.1mg0.1mg£626.00
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Further Information

Additional Names:
TNFRSF12A, FGF-inducible 14, FN14, TweakR, CD266
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Tumor necrosis factor receptor superfamily member 12A (TNFRSF12A) is also known as Fibroblast growth factor-inducible immediate-early response protein 14 (FN14 or FGF-inducible 14), Tweak-receptor, CD antigen CD266. TNFRSF12A contains one TNFR-Cys repeat. TNFRSF12A is highly expressed in heart, placenta and kidney. TNFRSF12A is receptor for TNFSF12/TWEAK, and is weak inducer of apoptosis in some cell types. TNFRSF12A / FN14 promotes angiogenesis and the proliferation of endothelial cells.
Background References:
  • Wiley S.R., et al., 2001, Immunity 15:837-846.
  • He F., et al., 2009, Protein Sci. 18:650-656.
Biological Activity:
Measured by its ability to bind CD155 in a functional ELISA.
Buffer:
50 mM tris, 100 mM glycine, pH7.5
Fusion Tag:
N-Fc Tag
NCBI Gene ID #:
51330
NCBI Official Name:
tumor necrosis factor receptor superfamily, member 12A
NCBI Official Symbol:
TNFRSF12A
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
33 kDa
Protein Accession #:
AAH02718
Purity:
>95% as determined by SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
Q9NP84

Documents