ProSci

S100A6 Recombinant Protein

Product Code:
 
PSI-96-668
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
 

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PSI-96-668-0.1mg0.1mg£560.00
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Further Information

Additional Names:
S100A6, 2A9, 5B10, CABP, CACY, PRA
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
S100 calcium binding protein A6 (S100-A6) is also kown as 2A9, 5B10, CABP, CACY and PRA, is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from the?neural crest, chondrocytes, macrophages, dendritic cells, etc. S100A6 may function in stimulation of Ca2+ -dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma. S100A6 has been shown to interact with S100B and SUGT1.
Background References:
  • Deloulme, J C, et al., 2000, J. Biol. Chem. (UNITED STATES) 275 (45): 35302?10.
  • Yang, Q, et al., 1999, Exp. Cell Res. (UNITED STATES) 246 (2): 501?9.
  • Nowotny, Marcin, et al., 2003, J. Biol. Chem. (United States) 278 (29): 26923?8.
Biological Activity:
The bio-activity of S100A6 was determined by its binding ability with human CEACAM3 protein in the presence of 100 mM CaCl2.
Buffer:
PBS, pH7.4
Fusion Tag:
Tag free
NCBI Gene ID #:
6277
NCBI Official Name:
S100 calcium binding protein A6
NCBI Official Symbol:
S100A6
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
10.2 kDa
Protein Accession #:
AAH01431
Purity:
>95% as determined by SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
P06703

Documents