ProSci

Jagged-1 Recombinant Protein

Product Code:
 
PSI-90-084
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
Working aliquots are stable for up to 3 months when stored at -20˚C.
 

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PSI-90-084-10ug10ug£469.00
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Further Information

Additional Names:
Protein Jagged-1, hJ1, CD339, JAG1
Application Note:
This recombinant proteins is for research use only.
Background:
Jagged-1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. It is involved in cell-fate decisions during hematopoiesis. Is involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. Enhances fibroblast growth factor-induced angiogenesis (in vitro). Defects in Jagged-1 are the cause of Alagille syndrome type 1 (ALGS1) and tetralogy of Fallot (TOF).
Biological Activity:
Inhibits adipogenesis of mesenchymal stem cells (MSCs). Induces Hes-1 in 3T3L-1 cells.
Buffer:
0.2um-filtered solution in PBS.
Concentration:
0.5mg/ml
Fusion Tag:
Fc Tag
NCBI Gene ID #:
182
NCBI Official Name:
jagged 1
NCBI Official Symbol:
JAG1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
P78504
Protein GI Number:
4557679
Purity:
>90% (SDS-PAGE).

Endotoxin level is less than 0.1EU/ μg purified protein (LAL test; Lonza).
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
P55083

Documents