ProSci

DcR3 Recombinant Protein

Product Code:
 
PSI-90-454
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
Stable for at least 1 year after receipt when stored at -20˚C. Working aliquots are stable for up to 3 months when stored at -20˚C.
 

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PSI-90-454-100ug100ug£686.00
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Further Information

Additional Names:
Decoy Receptor 3, Tumor Necrosis Factor Receptor Superfamily Member 6B, TNFRSF6B, M68
Application Note:
This recombinant proteins is for research use only.
Background:
Decoy receptor 3 (DcR3; TNFRSF6B; M68) is a member of the TNF receptor superfamily. DcR3 shares sequence identity with OPG (31%), TNF-RII (29%) and Fas (17%) and is expressed in a variety of different tissues and at high levels in many malignant tumors. Ligands of DcR3 include Fas ligand, homologous to lymphotoxin showing inducible expression and competing with HSV glycoprotein D for herpes virus entry mediator (a receptor expressed by T lymphocytes), TNF-like molecule 1A and heparan sulfate proteoglycans. DcR3 modulates the function of T cells, dendritic cells and macrophages. DcR3/Fc fusion proteins can bind to human and mouse B cells and suppress the activation of B cells.
Buffer:
Lyophilized from 0.2um-filtered solution in PBS. Reconstitute with 100 μl sterile water. Add 1X PBS to the desired protein concentration.
Fusion Tag:
Fc Tag
NCBI Gene ID #:
8771
NCBI Official Name:
tumor necrosis factor receptor superfamily, member 6b, decoy
NCBI Official Symbol:
TNFRSF6B
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
O95407
Protein GI Number:
4106877
Purity:
>98% (SDS-PAGE).

Endotoxin level is less than 0.06EU/ μg protein (LAL test; Lonza).
Recombinant Protein Sequence:
Thr32-Gly402
Source:
CHO cells
Swissprot #:
P29460

Documents