ProSci

PSA Recombinant Protein

Product Code:
 
PSI-92-336
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
 

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CodeSizePrice
PSI-92-336-0.05mg0.05mg£883.00
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Further Information

Additional Names:
Prostate-specific antigen, PSA, Gamma-seminoprotein, Kallikrein-3, P-30 antigen, Semenogelase, KLK3, APS, Kallikrein 3, KLK3
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
KLK3, also known as APS, is short for Prostate-specific antigen. It is a 261 aa. protein which belongs to the peptidase S1 family and Kallikrein subfamily. This protein has 5 isforms produced by alternative splicing. It is a secreted protein and can forms a heterodimer with SERPINA5 which can inhibit its activity. KLK3 is also strongly inhibited by Zn2+, 100 times more abundant in semen than in serum. This inhibition is relieved by exposure to semenogelins, which are avid zinc binders. KLK3 can hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.
Buffer:
Supplied as a 0.2 um filtered solution of 20mM TrisHcl, 150mM NaCl,1mM CaCl2,pH7.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Fusion Tag:
C-6 His tag
NCBI Gene ID #:
354
NCBI Official Name:
kallikrein related peptidase 3
NCBI Official Symbol:
KLK3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Predicted Molecular Weight:
27.1 kD
Protein Accession #:
P07288
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
Human Cells
Swissprot #:
P07288

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