ProSci

Angiopoietin-2 Recombinant Protein

Product Code:
 
PSI-90-295
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Storage:
 
Stable for at least 6 months after receipt when stored at -20˚C.
 

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PSI-90-295-10ug10ug£505.00
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Further Information

Additional Names:
Ang-2, Ang2, Angpt2
Application Note:
This recombinant proteins is for research use only.
Background:
Angiopoietin-1 (Ang-1) and Angiopoietin-2 (Ang-2) are closely related secreted ligands which bind with similar affinity to Tie-2. Tie-2 and angiopoietins have been shown to play critical roles in embryogenic angiogenesis and in maintaining the integrity of the adult vasculature. Ang-1 activates Tie-2 signaling on endothelial cells to promote chemotaxis, cell survival, cell sprouting, vessel growth and stabilization. Ang-2 has been identified as a secreted protein ligand of Tie-2 and has alternatively been reported to be an antagonist for Ang-1 induced Tie-2 signaling as well as an agonist for Tie-2 signaling, depending on the cell context.
Buffer:
Contains PBS with trehalose and Brij35. Reconstitute with 100 μl sterile water.
Concentration:
0.1 mg /ml after reconstitution.
Fusion Tag:
DDDDK Tag
NCBI Gene ID #:
285
NCBI Official Name:
angiopoietin 2
NCBI Official Symbol:
ANGPT2
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
O15123
Protein GI Number:
4557315
Purity:
>95% (SDS-PAGE).

Endotoxin level is less than 0.01EU/ μg purified protein (LAL test; Lonza).
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
P05230

Documents