ProSci

Casein kinase I gamma-2 Recombinant Protein

Product Code:
 
PSI-92-197
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
 

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CodeSizePrice
PSI-92-197-0.05mg0.05mg£673.00
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This product comes from: United States.
Typical lead time: 14-21 working days.
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Further Information

Additional Names:
Casein kinase I isoform gamma-2, CK1G2, CSNK1G2
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
CSNK1G2 is a cytoplasmic protein which contains one protein kinase domain. It is amember of the CK1 Ser/Thr protein kinase family of the large casein kinase I (CKI) subfamily. CSNK1G2 participates in Wnt signaling, involves in brain development and vesicular trafficking and neurotransmitter releasing from small synaptic vesicles. It regulates fast synaptic transmission mediated by glutamate. SMAD3 phosphorylation promotes its ligand-dependent ubiquitination and subsequent proteasome degradation, thus inhibiting SMAD3-mediated TGF-beta responses.
Buffer:
Supplied as a 0.2 um filtered solution of 20mM Tris,500mM NaCl,10%Glycerol,1mM DTT, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Fusion Tag:
N-6 His tag
NCBI Gene ID #:
1455
NCBI Official Name:
casein kinase 1 gamma 2
NCBI Official Symbol:
CSNK1G2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Predicted Molecular Weight:
47.6 kD
Protein Accession #:
P78368
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
P78368

Documents