ProSci

UFM1 activating enzyme Recombinant Protein

Product Code:
 
PSI-92-228
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
 

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PSI-92-228-0.05mg0.05mg£673.00
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Further Information

Additional Names:
Ubiquitin-like modifier-activating enzyme 5, ThiFP1, UFM1-activating enzyme, Ubiquitin-activating enzyme E1 domain-containing protein 1, UBE1DC1, UBA5
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
UBA5 is a member of the ubiquitin-activating E1 family and UBA5 subfamily. Ubiquitin and ubiquitin-like proteins are recognized as covalently conjugated to various cellular substrates by a three-step enzymatic pathway. The ubiquitin-activating enzyme (E1) has a vital role in the first step of ubiquitination pathway to activate ubiquitin or ubiquitin-like proteins. UBA5 activates ubiquitin-fold modifier 1, a ubiquitin-like post-translational modifier protein, via the formation of a high-energy thioester bond. UBA5 is located primarily in cytoplasm, while it generally localizes to the nucleus in presence of SUMO2.
Buffer:
Supplied as a 0.2 um filtered solution of 20mM TrisHCl pH 8.0,1mM DTT, 10% glycerol, 50mM NaCl. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Fusion Tag:
N-6 His tag
NCBI Gene ID #:
79876
NCBI Official Name:
ubiquitin like modifier activating enzyme 5
NCBI Official Symbol:
UBA5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Predicted Molecular Weight:
47 kD
Protein Accession #:
Q9GZZ9
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
Q9GZZ9

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