SUMO1 Recombinant Protein
Storage:
Lyophilized protein should be stored at -20˚C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7˚C for 2-7 days.
Aliquots of reconstituted samples are stable at -20˚C for 3 months.
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This product comes from:
United States.
Typical lead time:
14-21 working days.
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Further Information
Small Ubiquitin-Related Modifier 1, SUMO-1, GAP-Modifying Protein 1, GMP1, SMT3 Homolog 3, Sentrin, Ubiquitin-Homology Domain Protein PIC1, Ubiquitin-Like Protein SMT3C, Smt3C, Ubiquitin-Like Protein UBL1, SUMO1, SMT3H3, UBL1
This recombinant protein can be used for biological assays. For research use only.
Small Ubiquitin-Related Modifier 1 (SUMO1) is an Ubiquitin-like protein that belongs to the ubiquitin family with SUMO subfamily. It is a family of small, related proteins that can be enzymatically attached to a target protein by a post-translational modification process termed sumoylation. SUMO1 functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. SUMO1 is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. SUMO1 is not active until the last four amino acids of the carboxy-terminus are cleaved off. Polymeric SUMO1 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins and may also regulate a network of genes involved in palate development.
Lyophilized from a 0.2 um filtered solution of 50mM TrisHCl, 100mM NaCl, 1mM DTT, pH 8.5 . It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
N-6 His tag
7341
small ubiquitin-like modifier 1
SUMO1
Homo sapiens
Lyophilized
Predicted Molecular Weight:
13.7 kD
P63165
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
E. coli
P63165
