ProSci

Neutrophil cytosol factor 1 Recombinant Protein

Product Code:
 
PSI-92-514
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
Lyophilized protein should be stored at -20˚C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7˚C for 2-7 days.
Aliquots of reconstituted samples are stable at -20˚C for 3 months.
 

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PSI-92-514-0.05mg0.05mg£753.00
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Further Information

Additional Names:
NCF-1/47 kDa autosomal chronic granulomatous disease protein/47 kDa neutrophil oxidase factor/NCF-47K/Neutrophil NADPH oxidase factor 1/Nox organizer 2/Nox-organizing protein 2/SH3 and PX domain-containing protein 1A/p47-phox, NCF1
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Neutrophil cytosol factor 1( NCF1) is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is characterized as a multicomponent enzyme which is activated to produce superoxide anion. NCF2, NCF1, and a membrane bound cytochrome b558 are required for the activation of the latent NADPH oxidase. The human NCF1 gene encodes a 390 amino acids protein without a signal peptide. The NCF1 gene interacts with other subunits of nicotinamide adenine dinucleotide phosphate-oxidase (NADPH) and plays an important role in innate immunity, producing reactive oxygen species and reducing the severity and duration of parasitic infection and autoimmune disease. NCF1 also has a role in T cell activation.
Buffer:
Lyophilized from a 0.2 um filtered solution of 20mM Tris pH8.0,1mM DTT,0.1M NaCl. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Fusion Tag:
Tag Free
NCBI Gene ID #:
653361
NCBI Official Name:
neutrophil cytosolic factor 1
NCBI Official Symbol:
NCF1
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
45.6 kD
Protein Accession #:
P14598
Protein GI Number:
524552373
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
P14598

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