ProSci

TNF RII Recombinant Protein

Product Code:
 
PSI-92-700
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
Lyophilized protein should be stored at -20˚C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7˚C for 2-7 days.
Aliquots of reconstituted samples are stable at -20˚C for 3 months.
 

No additional charges, what you see is what you pay! *

CodeSizePrice
PSI-92-700-0.05mg0.05mg£597.00
Quantity:
Prices exclude any Taxes / VAT
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 14-21 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • Show All

Further Information

Additional Names:
Tumor necrosis factor receptor superfamily member 1B, TNFRSF1B, Tumor necrosis factor receptor 2, TNF-R2, TNF-RII, Tumor necrosis factor receptor type II, p75, p80 TNF-alpha receptor, CD120b
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Tumor necrosis factor receptor superfamily member 1B (TNFRSF1B) is a member of the tumor necrosis factor receptor superfamily. Human TNF RII contains four cysteinerich repeats in its ECD, which shares 58% and 56% amino acid sequence identity with the mouse and rat orthologs, respectively.TNF RII is expressed predominantly on cells of the hematopoietic lineage, such as T and natural killer cells, as well as on endothelial cells, microglia, astrocytes,neurons, oligodendrocytes, cardiac myocytes, thymocytes, and mesenchymal stem cells.TNF RII binds to the membranebound forms of TNF alpha and Lymphotoxin alpha/TNF beta soluble TNF is thought to signal predominately through TNF RI.Soluble TNF RII is believed to inhibit TNF biological activity by binding TNF thereby preventing it from activating membrane TNF receptors.
Buffer:
Lyophilized from a 0.2 um filtered solution of PBS, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH4O.
Fusion Tag:
C-Fc tag
NCBI Gene ID #:
7133
NCBI Official Name:
tumor necrosis factor receptor superfamily member 1B
NCBI Official Symbol:
TNFRSF1B
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
51.9 kD
Protein Accession #:
P20333
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
Human Cells
Swissprot #:
P20333

Documents