ProSci

High mobility group protein B1 Recombinant Protein

Product Code:
 
PSI-92-282
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
Lyophilized protein should be stored at -20˚C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7˚C for 2-7 days.
Aliquots of reconstituted samples are stable at -20˚C for 3 months.
 

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CodeSizePrice
PSI-92-282-0.05mg0.05mg£657.00
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Further Information

Additional Names:
High Mobility Group Protein B1, High Mobility Group Protein 1, HMG-1, HMGB1, HMG1
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
High mobility group protein B1 is a member of the HMGB family consisting of three members, HMGB1, HMGB2 and HMGB3.It Contains 2 HMG box DNA-binding domains entitled box A and box B and It is a highly negative-charged C terminus. As a nuclear protein, HMGB1 stabilizes nucleosomes and allows bending of DNA that facilitates gene transcription which is essential for individual survival. Meanwhile, it is revealed that HMGB1 can also act as a cytokine extracellularlly and regulates monocyte, T cell, dendritic cell activities in inflammatory responses.
Buffer:
Lyophilized from a 0.2 um filtered solution of 50mM HEPES-Na,p H 7.9, 500mM NaCl, 0.6mM DTT. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Fusion Tag:
N-MARI tag
NCBI Gene ID #:
3146
NCBI Official Name:
high mobility group box 1
NCBI Official Symbol:
HMGB1
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
10 kD
Protein Accession #:
P09429
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
P09429

Documents