ProSci

Fructose-1,6-Bisphosphatase 1 Recombinant Protein

Product Code:
 
PSI-91-122
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
 

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PSI-91-122-0.05mg0.05mg£594.00
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Further Information

Additional Names:
Fructose-1, 6-Bisphosphatase 1, FBPase 1, D-Fructose-1, 6-Bisphosphate 1-Phosphohydrolase 1, FBP1, FBP
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Fructose-1,6-Bisphosphatase 1 (FBPase 1) is a member of the FBPase class 1 family. FBPase 1 is a gluconeogenesis regulatory protein, which catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. FBPase 1 can assume an active R-state, or an inactive T-state. FBPase 1 deficiency is inherited as an autosomal recessive disorder mainly in the liver and causes life-threatening episodes of hypoglycemia and metabolic acidosis in newborn infants or young children. FBPase 1 coupled with phosphofructokinase (PFK) is involved in the metabolism of pancreatic islet cells.
Buffer:
Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 200mM NaCl, 1mM DTT, 1mM EDTA, 20% Glycerol, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Fusion Tag:
C-6 His tag
NCBI Gene ID #:
2203
NCBI Official Name:
fructose-bisphosphatase 1
NCBI Official Symbol:
FBP1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Predicted Molecular Weight:
37.89 kD
Protein Accession #:
P09467
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
P09467

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