ProSci

PPP1R1A Recombinant Protein

Product Code:
 
PSI-91-143
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
 

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PSI-91-143-0.05mg0.05mg£673.00
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Further Information

Additional Names:
Protein Phosphatase 1 Regulatory Subunit 1A, Protein Phosphatase Inhibitor 1, I-1, IPP-1, PPP1R1A, IPP1
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Protein Phosphatase 1 Regulatory Subunit 1A (PPP1R1A) is an inhibitor of protein-phosphatase 1. PPP1R1A is a cellular regulator of eIF2 alpha phosphorylation. In hormonal control of glycogen metabolism, IPP-1 protein plays important function. Hormones can elevate intracellular cAMP level and elevate IPP-1 activity. PPP1R1A activation caused cAMP increase , cAMP control over proteins that are not directly phosphorylated by PKA following a rise in intracellular calcium. IPP-1 is inactivated by calcineurin (PP2B). Multiple domains in IPP-1 target cellular PP1 complexes.
Buffer:
Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 150mM NaCl, 1mM DTT, 50% Glycerol, pH 8.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Fusion Tag:
C-6 His tag
NCBI Gene ID #:
5502
NCBI Official Name:
protein phosphatase 1 regulatory inhibitor subunit 1A
NCBI Official Symbol:
PPP1R1A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Predicted Molecular Weight:
19.98 kD
Protein Accession #:
Q13522
Protein GI Number:
767904139
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
Q13522

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