ProSci

Podoplanin Recombinant Protein

Product Code:
 
PSI-91-788
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
Lyophilized protein should be stored at -20˚C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7˚C for 2-7 days.
Aliquots of reconstituted samples are stable at -20˚C for 3 months.
 

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PSI-91-788-0.05mg0.05mg£597.00
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This product comes from: United States.
Typical lead time: 14-21 working days.
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Further Information

Additional Names:
Podoplanin, Aggrus, Glycoprotein 36, Gp36, PA2.26 Antigen, T1-Alpha, T1A, PDPN
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Podoplanin is a type-1 transmembrane protein that belongs to Podoplanin family. PDPN expressed in various specialized cell types throughout the body. It highly expressed in placenta, lung, skeletal muscle and brain, weakly expressed in brain, kidney and liver. In placenta, PDPN expressed on the apical plasma membrane of endothelium, in lung, expressed in alveolar epithelium. PDPN physiological function is related to its mucin-type character. PDPN may be involved in cell migration and/or actin cytoskeleton organization. When expressed in keratinocytes, induces changes in cell morphology with transfected cells showing an elongated shape, numerous membrane protrusions, and major reorganization of the actin cytoskeleton, increased motility and decreased cell adhesion. It requires for normal lung cell proliferation and alveolus formation at birth and Induces platelet aggregation. Nevertheless, it doesn?t have any effect on amino acid transport and the aquaporin-type water channels.
Buffer:
Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4 . It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Fusion Tag:
C-Fc tag
NCBI Gene ID #:
10630
NCBI Official Name:
podoplanin
NCBI Official Symbol:
PDPN
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
12.1 kD
Protein Accession #:
Q86YL7
Protein GI Number:
929654682
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
Human Cells
Swissprot #:
Q86YL7

Documents