ProSci

Carbonic Anhydrase 4 Recombinant Protein

Product Code:
 
PSI-91-092
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
 

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PSI-91-092-0.05mg0.05mg£883.00
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Further Information

Additional Names:
Carbonic Anhydrase 4, Carbonate Dehydratase IV, Carbonic Anhydrase IV, CA-IV, CA4
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Carbonic Anhydrase 4 (CA4) belongs to the alpha-carbonic anhydrase family. Alpha-carbonic anhydrase is a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. Carbonic anhydrase 4 is a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary (and certain other) capillaries and proximal renal tubules. Carbonic anhydrase 4 may stimulate the sodium/bicarbonate transporter activity of SLC4A4 that acts in pH homeostasis. It may have a role in inherited renal abnormalities of bicarbonate transport. Furthermore, Carbonic anhydrase 4 is essential for acid overload removal from the retina and retina epithelium and acid release in the choriocapillaris.
Buffer:
Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 100mM NaCl, pH 8.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Fusion Tag:
C-6 His tag
NCBI Gene ID #:
762
NCBI Official Name:
carbonic anhydrase 4
NCBI Official Symbol:
CA4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Predicted Molecular Weight:
31.43 kD
Protein Accession #:
P22748
Protein GI Number:
578877726
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
P22748

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