ProSci

beta-Defensin 1 Recombinant Protein

Product Code:
 
PSI-91-108
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
Lyophilized protein should be stored at -20˚C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7˚C for 2-7 days.
Aliquots of reconstituted samples are stable at -20˚C for 3 months.
 

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PSI-91-108-0.05mg0.05mg£657.00
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This product comes from: United States.
Typical lead time: 14-21 working days.
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Further Information

Additional Names:
Beta-Defensin 1, BD-1, hBD-1, Defensin Beta 1, DEFB1, BD1, HBD1
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
beta -Defensin 1 (DEFB1) is a member of the beta -defensin family, which is highly expressed by epithelial cells. beta -defensins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal peptide. beta -defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. beta -defensin 1 is an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. Defects in beta -Defensin-1 contribute to asthma diagnosis, with apparent gender-specific effects in human. beta -defensin 1 may also play a role in the pathogenesis of severe sepsis. In addition, beta -defensin 1 is associated with induction profiles in gingival keratinocytes.
Buffer:
Lyophilized from a 0.2 um filtered solution of 20mM PB, 130mM NaCl, pH 7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Fusion Tag:
Tag Free
NCBI Gene ID #:
1672
NCBI Official Name:
defensin beta 1
NCBI Official Symbol:
DEFB1
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
5.07 kD
Protein Accession #:
P60022
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
P60022

Documents