ProSci

N-Glycosylase Recombinant Protein

Product Code:
 
PSI-91-111
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
 

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CodeSizePrice
PSI-91-111-0.05mg0.05mg£673.00
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Further Information

Additional Names:
N-Glycosylase/DNA Lyase, 8-Oxoguanine DNA Glycosylase, DNA-(Apurinic or Apyrimidinic Site) Lyase, AP Lyase, OGG1, MMH, MUTM, OGH1
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Human N-Glycosylase/DNA Lyase is a DNA repair enzyme, which incises DNA at 8-oxoG residues, and excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damage DNA. DGG1 has a beta -lyase activity that nicks DNA 3? to the lesion.
Buffer:
Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 100mM NaCl, 1mM DTT, 1mM EDTA, 50% Glycerol, pH 7.8. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Fusion Tag:
N-GST tag
NCBI Gene ID #:
4968
NCBI Official Name:
8-oxoguanine DNA glycosylase
NCBI Official Symbol:
OGG1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Predicted Molecular Weight:
65.07 kD
Protein Accession #:
O15527
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
O15527

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