ProSci

Inositol Monophosphatase 1 Recombinant Protein

Product Code:
 
PSI-91-214
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
 

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PSI-91-214-0.05mg0.05mg£883.00
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Further Information

Additional Names:
Inositol Monophosphatase 1, IMP 1, IMPase 1, Inositol-1(or 4)-Monophosphatase 1, Lithium-Sensitive Myo-Inositol Monophosphatase A1, IMPA1, IMPA, IIMPase 2
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Inositol Monophosphatase 1 (IMPA1) belongs to the inositol monophosphatase family. IMPA1 is responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides, IMPA1 can use myo-inositol-1,3-diphosphate, myo-inositol-1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2-AMP as substrates. IMPA1 has been implicated as the pharmacological target for lithium action in brain. IMPA1 shows magnesium-dependent phosphatase activity and is inhibited by therapeutic concentrations of lithium. In addition, IMPA1 plays a improtant role in intracellular signal transduction.
Buffer:
Supplied as a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.25. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Fusion Tag:
N-6 His tag
NCBI Gene ID #:
3612
NCBI Official Name:
inositol monophosphatase 1
NCBI Official Symbol:
IMPA1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Predicted Molecular Weight:
32.3 kD
Protein Accession #:
P29218
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
P29218

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