ProSci

Sorbitol Dehydrogenase Recombinant Protein

Product Code:
 
PSI-91-671
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
 

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PSI-91-671-0.05mg0.05mg£883.00
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Further Information

Additional Names:
Sorbitol Dehydrogenase, L-Iditol 2-Dehydrogenase, SORD
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Sorbitol dehydrogenase, also known as L-iditol 2-dehydrogenase and SORD, is a member of the zinc-containing alcohol dehydrogenase family. SORD exsits in a homotetramer and binds one zinc ion per subunit. SORD is expressed in kidney and epithelial cells of both benign and malignant prostate tissue. SORD can converts sorbitol to fructose and catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase to make up the sorbitol pathway. SORD is up-regulated by androgens and down-regulated by castration. SORD may play a role in the sperm motility by providing an energetic source for sperm.
Buffer:
Supplied as a 0.2 um filtered solution of 20mM TrisHCl,0.2M NaCl,5mM DTT,20% glycerol,pH8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Fusion Tag:
C-6 His tag
NCBI Gene ID #:
6652
NCBI Official Name:
sorbitol dehydrogenase
NCBI Official Symbol:
SORD
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Predicted Molecular Weight:
39.3 kD
Protein Accession #:
Q00796
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
Human Cells
Swissprot #:
Q00796

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