ProSci

PADI4 Recombinant Protein

Product Code:
 
PSI-92-065
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
 

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PSI-92-065-0.05mg0.05mg£883.00
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Further Information

Additional Names:
Protein-Arginine Deiminase Type-4, HL-60 PAD, Peptidylarginine Deiminase IV, Protein-arginine Deiminase type IV, PADI4, PADI5, PDI5, PDI4
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Protein-Arginine Deiminase Type-4 (PADI4) belongs to the Protein Arginine Deiminase family. PADI4 is expressed in eosinophils and neutrophils, but it is not expressed in peripheral monocytes or lymphocytes. PADI4 catalyzes the citrullination/deimination of arginine residues of proteins. In addition, PADI4 may play an important role in tumourigenesis. Genetic variations in PADI4 are a cause of susceptibility to rheumatoid arthritis (RA), which is a systemic inflammatory disease with autoimmune features and a complex genetic component.
Buffer:
Supplied as a 0.2 um filtered solution of 50mM Tris, 500mM NaCl, pH 7.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Fusion Tag:
N-6 His tag
NCBI Gene ID #:
23569
NCBI Official Name:
peptidyl arginine deiminase, type IV
NCBI Official Symbol:
PADI4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Predicted Molecular Weight:
76.2 kD
Protein Accession #:
Q9UM07
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
Q9UM07

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