ProSci

Bisphosphoglycerate Mutase Recombinant Protein

Product Code:
 
PSI-92-092
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
 

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PSI-92-092-0.05mg0.05mg£673.00
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Further Information

Additional Names:
Bisphosphoglycerate Mutase, BPGM, 2, 3-Bisphosphoglycerate Mutase Erythrocyte, 3-Bisphosphoglycerate Synthase, 3-Diphosphoglycerate Mutase, DPGM, BPG-Dependent PGAM
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Bisphosphoglycerate Mutase (BPGM) is a member of the Phosphoglycerate Mutase family and BPG-Dependent PGAM subfamily. BPGM is a multifunctional enzyme. BPGM catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. It also has phosphoglycerate phosphomutase activity. BPGM plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of 2,3-bisphosphoglycerate (2,3-BPG). Deficiency of BPGM increases the affinity of cells for oxygen and result in hemolytic anemia.
Buffer:
Supplied as a 0.2 um filtered solution of 20mM Tris, 1mM DTT, pH 8.0 . It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Fusion Tag:
C-6 His tag
NCBI Gene ID #:
669
NCBI Official Name:
bisphosphoglycerate mutase
NCBI Official Symbol:
BPGM
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Predicted Molecular Weight:
31 kD
Protein Accession #:
P07738
Protein GI Number:
767983919
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
P07738

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