ProSci

CD3 epsilon Recombinant Protein

Product Code:
 
PSI-92-708
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
Lyophilized protein should be stored at -20˚C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7˚C for 2-7 days.
Aliquots of reconstituted samples are stable at -20˚C for 3 months.
 

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PSI-92-708-0.05mg0.05mg£597.00
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Further Information

Additional Names:
T-Cell Surface Glycoprotein CD3 Epsilon Chain, T-Cell Surface Antigen T3/Leu-4 Epsilon Chain, CD3e, T3E
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
T-Cell Surface Glycoprotein CD3 epsilon Chain (CD3 epsilon ) is a single-pass type I membrane protein. CD3 epsilon contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3 epsilon is a polypeptide encoded by the CD3E gene on chromosome 11 in humans. The T cell receptor-CD3 complex (TCR/CD3 complex) is involved in T-cell development and several intracellular signal-transduction pathways. This complex is critical for T-cell development and function, and represents one of the most complex transmembrane receptors. The T cell receptor-CD3 complex is unique in having ten cytoplasmic immunoreceptor tyrosine-based activation motifs (ITAMs). TCR/CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
Buffer:
Lyophilized from a 0.2 um filtered solution of PBS, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Fusion Tag:
C-Fc tag
NCBI Gene ID #:
916
NCBI Official Name:
CD3e molecule
NCBI Official Symbol:
CD3E
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
38.7 kD
Protein Accession #:
P07766
Protein GI Number:
767983919
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
Human Cells
Swissprot #:
P07766

Documents