Abnova Corporation

CD45RB monoclonal antibody, clone PTPRC/1147

Product Code:
 
MAB13025
Product Group:
 
Primary Antibodies
Supplier:
 
Abnova Corporation
Host Type:
 
Mouse
Antibody Isotype:
 
IgG1, kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
PTPRC/1147
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Flow Cytometry
  • Immunofluorescence (IF)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
 
Store at 4°C.
 

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CodeSizePrice
MAB13025-100ug100 ug£488.00
Quantity:
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Further Information

Antigen Target Species:
Human
Form:
Liquid
Gene Alias:
B220|CD45|CD45R|GP180|LCA|LY5|T200
Gene Description:
protein tyrosine phosphatase, receptor type, C
Gene ID:
5788
Gene Name:
PTPRC
Immunogen:
Recombinant protein corresponding to full length human CD45RB.
Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Product Description:
Mouse monoclonal antibody raised against full length recombinant human CD45RB.
Recommend Dilutions:
Flow Cytometry (0.5-1 ug/million cells in 0.1 mL)
Immunofluorescence (0.5-1 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL)
Western Blot (0.5-1 ug/mL)
The optimal working dilution should be determined
Specificity:
CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45RB is expressed on mature B-lymphocytes and the majority of lymphomas and leukemias of B-cell origin.
Storage Buffer:
In 10 mM PBS (0.05% BSA, 0.05% sodium azide).