TGX-221
| Code | Size | Price |
|---|
| SYN-1089-M100 | 100 mg | Enquire |
Quantity:
| SYN-1089-M001 | 1 mg | £86.00 |
Quantity:
| SYN-1089-M005 | 5 mg | £133.00 |
Quantity:
| SYN-1089-M010 | 10 mg | £215.00 |
Quantity:
| SYN-1089-M050 | 50 mg | £643.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
TGX221
Appearance:
Solid.
CAS:
663619-89-4
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Hazards:
H303, H317, H333
InChi:
InChI=1S/C21H24N4O2/c1-15-12-18(16(2)22-17-6-4-3-5-7-17)21-23-19(13-20(26)25(21)14-15)24-8-10-27-11-9-24/h3-7,12-14,16,22H,8-11H2,1-2H3
InChiKey:
CPRAGQJXBLMUEL-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 663619-89-4. Formula: C21H24N4O2. MW: 364.5. TGX221 is a potent, cell permeable ATP-competitive inhibitor of PI3K, with selectivity for the p110beta isoform (IC(50) of 50nM).
Molecular Formula:
C21H24N4O2
Molecular Weight:
364.5
Package Type:
Plastic Vial
Precautions:
P261, P272, P280, P302, P352, P333, P313, P321, P363, P501
Product Description:
TGX221 is a potent, cell permeable ATP-competitive inhibitor of PI3K, with selectivity for the p110beta isoform (IC(50) of 50nM).
Purity:
>95%
Signal word:
Warning
Solubility Chemicals:
Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol.
Transportation:
Non-hazardous
UNSPSC Category:
Protein Kinase Modulators
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
Advantages of a selective beta-isoform phosphoinositide 3-kinase antagonist, an anti-thrombotic agent devoid of other cardiovascular actions in the rat: S.A. Sturgeon, et al.; Eur. J. Pharmacol. 587, 209 (2008)