Further Information
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform, PI3-kinase subunit beta, PI3K-beta, PI3Kbeta, PtdIns-3-kinase subunit beta, Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta, PtdIns-3-kinase subunit p110-beta, p110beta, PIK3CB, PIK3C1
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
- Brock, C., et al., J. Cell Biol. 160(1):89-99 (2003).
- Kossila, M., et al., Diabetes Care 26(1):179-182 (2003).
- Yart, A., et al., J. Biol. Chem. 277(24):21167-21178 (2002).
- Ueki, K., et al., Proc. Natl. Acad. Sci. U.S.A. 99(1):419-424 (2002).
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
This PI3KCB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 713-744 amino acids from the C-terminal region of human PI3KCB.
5291
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
PIK3CB
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
123 kDa
P42338
1171955
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Cancer,Cell Cycle,Immunology,Signal Transduction
P42338
Optimal dilutions for each application to be determined by the researcher.