Further Information
Mitogen-activated protein kinase 14, MAP kinase 14, MAPK 14, CRK1, Mitogen-activated protein kinase p38 alpha, MAP kinase p38 alpha, Mapk14, Crk1, Csbp1, Csbp2
For WB starting dilution is: 1:1000
Responds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. Plays a critical role in the production of some cytokines, for example IL-6. Required in mid-fetal development for the growth of embryo-derived blood vessels in the labyrinth layer of the placenta. Also plays an essential role in developmental and stress-induced erythropoiesis, through regulation of EPO gene expression.
- Pan, W.W., et al. J. Biol. Chem. 285(45):34348-34354(2010)
- Menon, M.B., et al. J. Biol. Chem. 285(43):33242-33251(2010)
- Chandrakesan, P., et al. J. Biol. Chem. 285(43):33485-33498(2010)
- Ferreiro, I., et al. J. Biol. Chem. 285(41):31819-31828(2010)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Rat
This Mouse Mapk14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-53 amino acids from the N-terminal region of mouse Mapk14.
26416
Mitogen-activated protein kinase 14
Mapk14
Mus musculus
Liquid
PREDICTED MOLECULAR WEIGHT:
41 kDa
P47811
This antibody is purified through a protein A column, followed by peptide affinity purification.
Cancer,Cell Cycle,Immunology,Signal Transduction,
P47811
Optimal dilutions for each application to be determined by the researcher.