Further Information
Tumor necrosis factor receptor superfamily member 1A, Tumor necrosis factor receptor 1, TNF-R1, Tumor necrosis factor receptor type I, TNF-RI, TNFR-I, p55, p60, CD120a, Tumor necrosis factor receptor superfamily member 1A, membrane form, Tumor necrosis factor-binding protein 1, TBPI, TNFRSF1A, TNFAR, TNFR1
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
The protein encoded by this gene is a member of the
TNF-receptor superfamily. This protein is one of the major
receptors for the tumor necrosis factor-alpha. This receptor can
activate NF-kappaB, mediate apoptosis, and function as a regulator
of inflammation. Antiapoptotic protein BCL2-associated athanogene 4
(BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to
interact with this receptor, and thus play regulatory roles in the
signal transduction mediated by the receptor. Germline mutations of
the extracellular domains of this receptor were found to be
associated with the autosomal dominant periodic fever syndrome. The
impaired receptor clearance is thought to be a mechanism of the
disease.
- Giroux, S., et al. Bone 47(5):975-981(2010)
- Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Wolanska, M., et al. Ginekol. Pol. 81(6):431-434(2010)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
This TNFR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 252-281 amino acids from human TNFR.
7132
Tumor necrosis factor receptor superfamily member 1A
TNFRSF1A
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
50 kDa
P19438
135959
This antibody is purified through a protein A column, followed by peptide affinity purification.
Cancer,Cell Cycle,Immunology,Signal Transduction,
P19438
Optimal dilutions for each application to be determined by the researcher.