Further Information
Cyclin-dependent kinase 1, CDK1, Cell division control protein 2 homolog, Cell division protein kinase 1, p34 protein kinase, CDK1, CDC2, CDC28A, CDKN1, P34CDC2
For WB starting dilution is: 1:1000
CDC2 is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of CDC2 is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control.
- Forester,C.M., Proc. Natl. Acad. Sci. U.S.A. 104 (50), 19867-19872 (2007)
- Skoufias,D.A., J. Cell Biol. 179 (4), 671-685 (2007)
- Hester,K.D., Cell Cycle(13), 1594-1604 (2007)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Xenopus, Mouse, Rat
This CDC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 213-241 amino acids from the C-terminal region of human CDC2.
983
Cyclin-dependent kinase 1
CDK1
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
34 kDa
P06493
334302921
This antibody is purified through a protein A column, followed by peptide affinity purification.
Cancer,Cell Cycle,Neuroscience
P06493
Optimal dilutions for each application to be determined by the researcher.