ProSci

MMP19 Antibody

Product Code:
 
PSI-57-250
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis of lysate from human placenta tissue lysate, using MMP19 Antibody at 1:1000 at each lane.
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Western blot analysis of lysate from human placenta tissue lysate, using MMP19 Antibody at 1:1000 at each lane.

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PSI-57-250-400ul400ul£626.00
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Further Information

Additional Names:
Matrix metalloproteinase-19, MMP-19, 3424-, Matrix metalloproteinase RASI, Matrix metalloproteinase-18, MMP-18, MMP19, MMP18, RASI
Application Note:
For WB starting dilution is: 1:1000
Background:
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This protein is expressed in human epidermis and it has a role in cellular proliferation as well as migration and adhesion to type I collagen. Multiple transcript variants encoding distict isoforms have been identified for this gene.
Background References:
  • Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :
  • Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
  • Romero, R., et al. Am. J. Obstet. Gynecol. 202 (5), 431 (2010) :
  • Muller, M., et al. Mod. Pathol. 23(4):511-521(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MMP19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-84 amino acids from the N-terminal region of human MMP19.
NCBI Gene ID #:
4327
NCBI Official Name:
Matrix metalloproteinase-19
NCBI Official Symbol:
MMP19
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
57 kDa
Protein Accession #:
Q99542
Protein GI Number:
12643345
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Signal Transduction
Swissprot #:
Q99542
User NOte:
Optimal dilutions for each application to be determined by the researcher.