ProSci

SCNN1B Antibody

Product Code:
 
PSI-60-822
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).
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Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).

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PSI-60-822-400ul400ul£626.00
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Further Information

Additional Names:
Amiloride-sensitive sodium channel subunit beta, Beta-NaCH, Epithelial Na(+) channel subunit beta, Beta-ENaC, ENaCB, Nonvoltage-gated sodium channel 1 subunit beta, SCNEB, SCNN1B
Application Note:
For WB starting dilution is: 1:1000
Background:
Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the beta subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), and Liddle syndrome.
Background References:
  • Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
  • Song, W., et al. J. Biol. Chem. 285(13):9716-9728(2010)
  • Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :
  • McGeachie, M., et al. Circulation 120(24):2448-2454(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SCNN1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 306-332 amino acids from the Central region of human SCNN1B.
NCBI Gene ID #:
6338
NCBI Official Name:
Amiloride-sensitive sodium channel subunit beta
NCBI Official Symbol:
SCNN1B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
73 kDa
Protein Accession #:
P51168
Protein GI Number:
8928561
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Obesity,Neuroscience,Signal Transduction
Swissprot #:
P51168
User NOte:
Optimal dilutions for each application to be determined by the researcher.