Further Information
Synaptosomal-associated protein 25, SNAP-25, Super protein, SUP, Synaptosomal-associated 25 kDa protein, SNAP25, SNAP
For WB starting dilution is: 1:1000
Synaptic vesicle membrane docking and fusion is mediated
by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment
protein receptors) located on the vesicle membrane (v-SNAREs) and
the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE
complex consists of a bundle of four helices, one of which is
supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on
the plasma membrane, the protein syntaxin supplies one helix and
the protein encoded by this gene contributes the other two.
Therefore, this gene product is a presynaptic plasma membrane
protein involved in the regulation of neurotransmitter release. Two
alternative transcript variants encoding different protein isoforms
have been described for this gene.
- Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
- Greaves, J., et al. J. Biol. Chem. 285(32):24629-24638(2010)
- Oner, O., et al.Atten Disord (2010) In press :
- Zhang, H., et al. Eur. J. Paediatr. Neurol. (2010) In press :
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Zebrafish, Bovine, Chicken, Mouse, Rat
This SNAP25 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-63 amino acids from the Central region of human SNAP25.
6616
Synaptosomal-associated protein 25
SNAP25
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
23 kDa
P60880
46397726
This antibody is purified through a protein A column, followed by peptide affinity purification.
Cancer,Obesity,Neuroscience,Signal Transduction
P60880
Optimal dilutions for each application to be determined by the researcher.