Further Information
ATP-binding cassette sub-family D member 1, Adrenoleukodystrophy protein, ALDP, ABCD1, ALD
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For FACS starting dilution is: 1:10~50
ABCD1 is a member of the
superfamily of ATP-binding cassette (ABC) transporters. ABC
proteins transport various molecules across extra- and
intra-cellular membranes. ABC genes are divided into seven distinct
subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This
protein is a member of the ALD subfamily, which is involved in
peroxisomal import of fatty acids and/or fatty acyl-CoAs in the
organelle. All known peroxisomal ABC transporters are half
transporters which require a partner half transporter molecule to
form a functional homodimeric or heterodimeric transporter. This
peroxisomal membrane protein is likely involved in the peroxisomal
transport or catabolism of very long chain fatty acids. Defects in
this gene have been identified as the underlying cause of
adrenoleukodystrophy, an X-chromosome recessively inherited
demyelinating disorder of the nervous system.
- Matsukawa, T., et al. Neurogenetics (2010) In press :
- Xie, H.H., et al. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 27(2):144-148(2010)
- Li, J.Y., et al. J. Neurol. Sci. 290 (1-2), 163-165 (2010) :
- Hour, T.C., et al. Int. J. Biol. Markers 24(3):171-178(2009)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Mouse
This ABCD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 257-285 amino acids from the Central region of human ABCD1.
215
ATP-binding cassette sub-family D member 1
ABCD1
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
83 kDa
P33897
67476960
This antibody is purified through a protein A column, followed by peptide affinity purification.
Cancer,Obesity,Signal Transduction
P33897
Optimal dilutions for each application to be determined by the researcher.