ProSci

SEL1L Antibody

Product Code:
 
PSI-55-340
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Fluorescence-activated cell sorting (FACS)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
1 / 3
Western blot analysis in MCF-7 cell line lysates (35ug/lane).
2 / 3
SEL1L antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
3 / 3
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Western blot analysis in MCF-7 cell line lysates (35ug/lane).
SEL1L antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

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PSI-55-340-400ul400ul£626.00
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Further Information

Additional Names:
Protein sel-1 homolog 1, Suppressor of lin-12-like protein 1, Sel-1L, SEL1L, TSA305
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

For FACS starting dilution is: 1:10~50
Background:
May play a role in Notch signaling (By similarity). May be involved in the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins.
Background References:
  • Ban, H.J., et al. BMC Genet. 11, 26 (2010) :
  • Riemer, J., et al. Proc. Natl. Acad. Sci. U.S.A. 106(35):14831-14836(2009)
  • Cormier, J.H., et al. Mol. Cell 34(5):627-633(2009)
  • Oresic, K., et al. Biosci. Rep. 29(3):173-181(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SEL1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-182 amino acids from the Central region of human SEL1L.
NCBI Gene ID #:
6400
NCBI Official Name:
Protein sel-1 homolog 1
NCBI Official Symbol:
SEL1L
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
89 kDa
Protein Accession #:
Q9UBV2
Protein GI Number:
62512184
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Signal Transduction
Swissprot #:
Q9UBV2
User NOte:
Optimal dilutions for each application to be determined by the researcher.