ProSci

CCKAR Antibody

Product Code:
 
PSI-60-512
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in human placenta tissue lysates (35ug/lane).
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Western blot analysis in human placenta tissue lysates (35ug/lane).

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PSI-60-512-400ul400ul£626.00
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Further Information

Additional Names:
Cholecystokinin receptor type A, CCK-A receptor, CCK-AR, Cholecystokinin-1 receptor, CCK1-R, CCKAR, CCKRA
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a G-protein coupled receptor that binds non-sulfated members of the cholecystokinin (CCK) family of peptide hormones. This receptor is a major physiologic mediator of pancreatic enzyme secretion and smooth muscle contraction of the gallbladder and stomach. In the central and peripheral nervous system this receptor regulates satiety and the release of beta-endorphin and dopamine.
Background References:
  • Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
  • Cong, P., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 299 (3), G742-G750 (2010) :
  • Tiwari, A.K., et al. Prog. Neuropsychopharmacol. Biol. Psychiatry (2010) In press :
  • Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CCKAR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-257 amino acids from the Central region of human CCKAR.
NCBI Gene ID #:
886
NCBI Official Name:
Cholecystokinin receptor type A
NCBI Official Symbol:
CCKAR
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
48 kDa
Protein Accession #:
P32238
Protein GI Number:
416772
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,Growth Factor
Swissprot #:
P32238
User NOte:
Optimal dilutions for each application to be determined by the researcher.