ProSci

CNGB3 Antibody

Product Code:
 
PSI-56-597
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in MDA-MB435 cell line lysates (35ug/lane).
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Western blot analysis in MDA-MB435 cell line lysates (35ug/lane).

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PSI-56-597-400ul400ul£626.00
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Further Information

Additional Names:
Cyclic nucleotide-gated cation channel beta-3, Cone photoreceptor cGMP-gated channel subunit beta, Cyclic nucleotide-gated cation channel modulatory subunit, Cyclic nucleotide-gated channel beta-3, CNG channel beta-3, CNGB3
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes the beta subunit of a cyclic nucleotide-gated ion channel. The encoded beta subunit appears to play a role in modulation of channel function in cone photoreceptors. This heterotetrameric channel is necessary for sensory transduction, and mutations in this gene have been associated with achromatopsia 3, progressive cone dystrophy, and juvenile macular degeneration, also known as Stargardt Disease.
Background References:
  • Komaromy, A.M., et al. Hum. Mol. Genet. 19(13):2581-2593(2010)
  • Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
  • Thiadens, A.A., et al. Ophthalmology 117(4):825-830(2010)
  • Azam, M., et al. Mol. Vis. 16, 774-781 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CNGB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-55 amino acids from the N-terminal region of human CNGB3.
NCBI Gene ID #:
54714
NCBI Official Name:
Cyclic nucleotide-gated cation channel beta-3
NCBI Official Symbol:
CNGB3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
92 kDa
Protein Accession #:
Q9NQW8
Protein GI Number:
311033366
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,Signal Transduction
Swissprot #:
Q9NQW8
User NOte:
Optimal dilutions for each application to be determined by the researcher.