Further Information
Voltage-dependent calcium channel subunit alpha-2/delta-3, Voltage-gated calcium channel subunit alpha-2/delta-3, Voltage-dependent calcium channel subunit alpha-2-3, Voltage-dependent calcium channel subunit delta-3, CACNA2D3
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
CACNA2D3 is a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits.
- Trynka, G., et al. Gut 58(8):1078-1083(2009)
- Wanajo, A., et al. Gastroenterology 135(2):580-590(2008)
- Uhl, G.R., et al. Arch. Gen. Psychiatry 65(6):683-693(2008)
- Abo-Dalo, B., et al. Am. J. Med. Genet.143A (22), 2668-2674 (2007)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Mouse, Rat
This CACNA2D3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1026-1053 amino acids from the C-terminal region of human CACNA2D3.
55799
Voltage-dependent calcium channel subunit alpha-2/delta-3
CACNA2D3
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
123 kDa
Q8IZS8
74723683
This antibody is purified through a protein A column, followed by peptide affinity purification.
Neuroscience,Signal Transduction
Q8IZS8
Optimal dilutions for each application to be determined by the researcher.