Further Information
Carbohydrate sulfotransferase 5, 282-, Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 4-alpha, GST4-alpha, Intestinal N-acetylglucosamine-6-O-sulfotransferase, I-GlcNAc6ST, Intestinal GlcNAc-6-sulfotransferase, hIGn6ST, N-acetylglucosamine 6-O-sulfotransferase 3, GlcNAc6ST-3, Gn6st-3, CHST5
For WB starting dilution is: 1:1000
The carbohydrates of glycoconjugates are highly diverse
structures with variation in monosaccharide composition, glycosidic
linkage positions, and branching of chains. Further diversity is
added by the covalent addition of sulfate moieties to particular
hydroxyl groups and amino groups of saccharides. The sulfate
modifications of glycoproteins can be extensive in amount and
frequently occur at high density. They can have a profound effect
on the physiochemical properties of the glycoconjugates, at least
in part through the addition of negative charge. Carbohydrate
sulfation plays a critical role in many biologic processes. CHST5
belongs to the GST family of sulfotransferases, which also includes
CHST1 (MIM 603797), CHST2 (MIM 603798), CHST3 (MIM 603799), and
LSST. These enzymes are 6-O-sulfotransferases, which add sulfate to
C6 of galactose (Gal), N-acetylgalactosamine (GalNAc), or
N-acetylglucosamine (GlcNAc) (Lee et al., 1999 [PubMed
10491328]).
- Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)
- Dastani, Z., et al. Eur. J. Hum. Genet. 18(3):342-347(2010)
- Saito, A., et al. J. Hum. Genet. 54(6):317-323(2009)
- Kitayama, K., et al. J. Biol. Chem. 282(41):30085-30096(2007)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
This CHST5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 275-302 amino acids from the C-terminal region of human CHST5.
23563
Carbohydrate sulfotransferase 5
CHST5
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
46 kDa
Q9GZS9
239938912
This antibody is purified through a protein A column, followed by peptide affinity purification.
Obesity,Neuroscience,Signal Transduction
Q9GZS9
Optimal dilutions for each application to be determined by the researcher.