ProSci

PNPO Antibody

Product Code:
 
PSI-63-923
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis of PNPO Antibody in 293 cell line lysates (35ug/lane)
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Western blot analysis of PNPO Antibody in 293 cell line lysates (35ug/lane)

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PSI-63-923-400ul400ul£626.00
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Further Information

Additional Names:
Pyridoxine-5'-phosphate oxidase, Pyridoxamine-phosphate oxidase, PNPO
Application Note:
For WB starting dilution is: 1:1000
Background:
The enzyme encoded by this gene catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine.
Background References:
  • Musayev, F.N., et al. J. Biol. Chem. 284(45):30949-30956(2009)
  • Khayat, M., et al. Mol. Genet. Metab. 94(4):431-434(2008)
  • Song, H., et al. Schizophr. Res. 97 (1-3), 264-270 (2007) :
  • Mills, P.B., et al. Hum. Mol. Genet. 14(8):1077-1086(2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PNPO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 232-261 amino acids from the C-terminal region of human PNPO.
NCBI Gene ID #:
55163
NCBI Official Name:
Pyridoxine-5'-phosphate oxidase
NCBI Official Symbol:
PNPO
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
30 kDa
Protein Accession #:
Q9NVS9
Protein GI Number:
37082126
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Neuroscience,Signal Transduction
Swissprot #:
Q9NVS9
User NOte:
Optimal dilutions for each application to be determined by the researcher.