ProSci

ODC1 Antibody

Product Code:
 
PSI-57-425
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in K562 cell line lysates (35ug/lane).
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Western blot analysis in K562 cell line lysates (35ug/lane).

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PSI-57-425-400ul400ul£626.00
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Further Information

Additional Names:
Ornithine decarboxylase, ODC, ODC1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter.
Background References:
  • Chaturvedi, R., et al. Gastroenterology 139(5):1686-1698(2010)
  • Zell, J.A., et al. J. Natl. Cancer Inst. 102(19):1513-1516(2010)
  • Geerts, D., et al. Int. J. Cancer 126(9):2012-2024(2010)
  • Hughes, D., et al. Colorectal Dis (2010) In press :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine
Immunogen:
This ODC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 323-352 amino acids from the C-terminal region of human ODC1.
NCBI Gene ID #:
4953
NCBI Official Name:
Ornithine decarboxylase
NCBI Official Symbol:
ODC1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
51 kDa
Protein Accession #:
P11926
Protein GI Number:
118377
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
P11926
User NOte:
Optimal dilutions for each application to be determined by the researcher.