ProSci

CTNS Antibody

Product Code:
 
PSI-60-528
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in HepG2 cell line lysates (35ug/lane).
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Western blot analysis in HepG2 cell line lysates (35ug/lane).

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PSI-60-528-400ul400ul£626.00
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Further Information

Additional Names:
Cystinosin, CTNS
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a seven-transmembrane domain protein that functions to transport cystine out of lysosomes. Its activity is driven by the H+ electrochemical gradient of the lysosomal membrane. Mutations in this gene cause cystinosis, a lysosomal storage disorder. Alternative splicing results in multiple transcript variants.
Background References:
  • Taranta, A., et al. Pediatr. Nephrol. 25(7):1263-1267(2010)
  • Bellomo, F., et al. Free Radic. Biol. Med. 48(7):865-872(2010)
  • Kumar, A., et al. J. Biosci. 35(1):21-25(2010)
  • Aldahmesh, M.A., et al. Ophthalmic Genet. 30(4):185-189(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CTNS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 341-367 amino acids from the C-terminal region of human CTNS.
NCBI Gene ID #:
1497
NCBI Official Name:
Cystinosin
NCBI Official Symbol:
CTNS
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
42 kDa
Protein Accession #:
O60931
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
O60931
User NOte:
Optimal dilutions for each application to be determined by the researcher.