Antibody Isotype:
Rabbit Ig
Antibody Clonality:
Polyclonal
Applications:- Fluorescence-activated cell sorting (FACS)
- Immunofluorescence (IF)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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This product comes from:
United States.
Typical lead time:
14-21 working days.
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- Further Information
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Further Information
Transcription factor A, mitochondrial, mtTFA, Mitochondrial transcription factor 1, MtTF1, Transcription factor 6, TCF-6, Transcription factor 6-like 2, TFAM, TCF6, TCF6L2
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For FACS starting dilution is: 1:10~50
For IF starting dilution is: 1:10~50
This gene encodes a mitochondrial transcription factor
that is a key activator of mitochondrial transcription as well as a
participant in mitochondrial genome replication. Studies in mice
have demonstrated that this gene product is required to regulate
the mitochondrial genome copy number and is essential for embryonic
development. A mouse model for Kearns-Sayre syndrome was produced
when expression of this gene was eliminated by targeted disruption
in heart and muscle cells.
- Wang, W., et al. Nucleic Acids Res. (2010) In press :
- Corneveaux, J.J., et al. Hum. Mol. Genet. 19(16):3295-3301(2010)
- Akhmetov, I.I., et al. Fiziol Cheloveka 36(2):121-125(2010)
- Shulman, J.M., et al. PLoS ONE(6), E11244 (2010) :
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
This TFAM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 216-246 amino acids from the C-terminal region of human TFAM.
7019
Transcription factor A, mitochondrial
TFAM
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
29 kDa
Q00059
417324
This antibody is purified through a protein A column, followed by peptide affinity purification.
Obesity,Signal Transduction
Q00059
Optimal dilutions for each application to be determined by the researcher.