ProSci

KRT72 Antibody

Product Code:
 
PSI-60-728
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in human Uterus tissue lysates (35ug/lane).
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Western blot analysis in human Uterus tissue lysates (35ug/lane).

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PSI-60-728-400ul400ul£626.00
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Further Information

Additional Names:
Keratin, type II cytoskeletal 72, Cytokeratin-72, CK-72, Keratin-72, K72, Type II inner root sheath-specific keratin-K6irs2, Type-II keratin Kb35, KRT72, K6IRS2, KB35, KRT6, KRT6IRS2
Application Note:
For WB starting dilution is: 1:1000
Background:
Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells. The type II keratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This gene encodes a type II keratin that is specifically expressed in the inner root sheath of hair follicles. The type II keratins are clustered in a region of chromosome 12q12-q13. Multiple transcript variants encoding different isoforms have been found for this gene.
Background References:
  • Bertheau, P., et al. PLoS Med.(3), E90 (2007) :
  • Schweizer, J., et al. J. Cell Biol. 174(2):169-174(2006)
  • Langbein, L., et al. J. Invest. Dermatol. 120(4):512-522(2003)
  • Porter, R.M., et al. Br. J. Dermatol. 145(4):558-568(2001)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine
Immunogen:
This KRT72 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 313-342 amino acids from the Central region of human KRT72.
NCBI Gene ID #:
140807
NCBI Official Name:
Keratin, type II cytoskeletal 72
NCBI Official Symbol:
KRT72
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
56 kDa
Protein Accession #:
Q14CN4
Protein GI Number:
166218813
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q14CN4
User NOte:
Optimal dilutions for each application to be determined by the researcher.