ProSci

PBXIP1 Antibody

Product Code:
 
PSI-58-760
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
1 / 2
Western blot analysis in NCI-H292 cell line lysates (35ug/lane).
2 / 2
Western blot analysis of PBXIP1 using rabbit polyclonal PBXIP1 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PBXIP1 gene.
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Western blot analysis in NCI-H292 cell line lysates (35ug/lane).
Western blot analysis of PBXIP1 using rabbit polyclonal PBXIP1 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PBXIP1 gene.

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PSI-58-760-400ul400ul£626.00
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Further Information

Additional Names:
Pre-B-cell leukemia transcription factor-interacting protein 1, Hematopoietic PBX-interacting protein, PBXIP1, HPIP
Application Note:
For WB starting dilution is: 1:1000
Background:
Regulator of pre-B-cell leukemia transcription factors (BPXs) function. Inhibits the binding of PBX1-HOX complex to DNA and blocks the transcriptional activity of E2A-PBX1. Tethers estrogen receptor-alpha (ESR1) to microtubules and allows them to influence estrogen receptors-alpha signaling.
Background References:
  • Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)
  • Olsen, J.V., et al. Cell 127(3):635-648(2006)
  • Lim, J., et al. Cell 125(4):801-814(2006)
  • Abramovich, C., et al. Oncogene 21(44):6766-6771(2002)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PBXIP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 472-501 amino acids from the C-terminal region of human PBXIP1.
NCBI Gene ID #:
57326
NCBI Official Name:
Pre-B-cell leukemia transcription factor-interacting protein 1
NCBI Official Symbol:
PBXIP1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
81 kDa
Protein Accession #:
Q96AQ6
Protein GI Number:
74751749
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q96AQ6
User NOte:
Optimal dilutions for each application to be determined by the researcher.