ProSci

TFEC Antibody

Product Code:
 
PSI-60-561
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).
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Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).

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PSI-60-561-400ul400ul£626.00
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Further Information

Additional Names:
Transcription factor EC, TFE-C, Class E basic helix-loop-helix protein 34, bHLHe34, Transcription factor EC-like, hTFEC-L, TFEC, BHLHE34, TCFEC, TFECL
Application Note:
For WB starting dilution is: 1:1000
Background:
Transcriptional regulator that acts as a repressor or an activator. Acts as a transcriptional repressor on minimal promoter containing element F (that includes an E-box sequence). Binds to element F in an E-box sequence-specific manner. Acts as a transcriptional transactivator on the proximal promoter region of the tartrate-resistant acid phosphatase (TRAP) E-box containing promoter (By similarity). Collaborates with MITF in target gene activation (By similarity). Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence (By similarity). Binds to mu E3 DNA sequence of the immunoglobulin heavy-chain gene enhancer (By similarity). Binds DNA in a homo-or heterodimeric form.
Background References:
  • Mansky, K.C., et al. J. Leukoc. Biol. 71(2):304-310(2002)
  • Chung, M.C., et al. Biochemistry 40(30):8887-8897(2001)
  • Steingrimsson, E., et al. Development 125(23):4607-4616(1998)
  • Yasumoto, K., et al. Biochim. Biophys. Acta 1353(1):23-31(1997)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Chicken, Mouse, Rat
Immunogen:
This TFEC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 179-205 amino acids from the Central region of human TFEC.
NCBI Gene ID #:
22797
NCBI Official Name:
Transcription factor EC
NCBI Official Symbol:
TFEC
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
39 kDa
Protein Accession #:
O14948
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
O14948
User NOte:
Optimal dilutions for each application to be determined by the researcher.