ProSci

LARP7 Antibody

Product Code:
 
PSI-56-783
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in WiDr cell line lysates (35ug/lane).

Western blot analysis in WiDr cell line lysates (35ug/lane).

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PSI-56-783-400ul400ul£626.00
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Further Information

Additional Names:
La-related protein 7, La ribonucleoprotein domain family member 7, P-TEFb-interaction protein for 7SK stability, PIP7S, LARP7
Application Note:
For WB starting dilution is: 1:1000
Background:
LARP7 is a negative transcriptional regulator of polymerase II genes, acting by means of the 7SK RNP system. Within the 7SK RNP complex, the positive transcription elongation factor b (P-TEFb) is sequestered in an inactive form, preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.
Background References:
  • Tyagi, M., et al. J. Virol. 84(13):6425-6437(2010)
  • Kalsi, G., et al. Hum. Mol. Genet. 19(12):2497-2506(2010)
  • Markert, A., et al. EMBO Rep. 9(6):569-575(2008)
  • Krueger, B.J., et al. Nucleic Acids Res. 36(7):2219-2229(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Monkey, Mouse, Rat
Immunogen:
This LARP7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 527-556 amino acids from the C-terminal region of human LARP7.
NCBI Gene ID #:
51574
NCBI Official Name:
La-related protein 7
NCBI Official Symbol:
LARP7
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
67 kDa
Protein Accession #:
Q4G0J3
Protein GI Number:
121945944
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q4G0J3
User NOte:
Optimal dilutions for each application to be determined by the researcher.