ProSci

XPA Antibody

Product Code:
 
PSI-57-303
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis of XPA using rabbit polyclonal XPA Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the XPA gene.
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Western blot analysis in WiDr cell line lysates (35ug/lane).
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Western blot analysis of XPA using rabbit polyclonal XPA Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the XPA gene.
Western blot analysis in WiDr cell line lysates (35ug/lane).

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PSI-57-303-400ul400ul£626.00
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Further Information

Additional Names:
DNA repair protein complementing XP-A cells, Xeroderma pigmentosum group A-complementing protein, XPA, XPAC
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a zinc finger protein involved in DNA excision repair. The encoded protein is part of the NER (nucleotide excision repair) complext which is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens. Mutations in this gene are associated with xeroderma pigmentosum complementation group A. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq].
Background References:
  • Palli, D., et al. Mutagenesis 25(6):569-575(2010)
  • Fan, W., et al. Mol. Cell 39(2):247-258(2010)
  • Ho-Pun-Cheung, A., et al. Pharmacogenomics J. (2010) In press :
  • Hsieh, Y.Y., et al. Anticancer Res. 30(6):2203-2208(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This XPA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 185-213 amino acids from the C-terminal region of human XPA.
NCBI Gene ID #:
7507
NCBI Official Name:
DNA repair protein complementing XP-A cells
NCBI Official Symbol:
XPA
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
31 kDa
Protein Accession #:
P23025
Protein GI Number:
139816
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P23025
User NOte:
Optimal dilutions for each application to be determined by the researcher.