ProSci

FUT3 Antibody

Product Code:
 
PSI-63-932
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis of FUT3 Antibody in A2058 cell line lysates (35ug/lane)
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Western blot analysis of FUT3 Antibody in A2058 cell line lysates (35ug/lane)

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PSI-63-932-400ul400ul£626.00
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Further Information

Additional Names:
Galactoside 3(4)-L-fucosyltransferase, Blood group Lewis alpha-4-fucosyltransferase, Lewis FT, Fucosyltransferase 3, Fucosyltransferase III, FucT-III, FUT3, FT3B, LE
Application Note:
For WB starting dilution is: 1:1000
Background:
FUT3 comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This protein is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities.
Background References:
  • Park, H.D., et al. KoreanLab Med 30(1):51-57(2010)
  • Matzhold, E.M., et al. Transfusion 49(10):2097-2108(2009)
  • Norden, R., et al. Glycobiology 19(7):776-788(2009)
  • Liu, J., et al. J. Exp. Clin. Cancer Res. 28, 154 (2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This FUT3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 288-315 amino acids from the C-terminal region of human FUT3.
NCBI Gene ID #:
2525
NCBI Official Name:
Galactoside 3(4)-L-fucosyltransferase
NCBI Official Symbol:
FUT3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
42 kDa
Protein Accession #:
P21217
Protein GI Number:
121137
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P21217
User NOte:
Optimal dilutions for each application to be determined by the researcher.